This proposed project will help resolve both plastics crises for labs and trainees at UIUC and elsewhere, by developing and promoting affordable, scalable, SUP reuse protocols for a wider range of products. This project is requesting funds to develop and test three lines of protocols for polypropylene (PP) and polysturene (PS) reuse and replacement !) slight modification of a highthroughout PP tip washing and reuse system (modified protocol using TipNovusmini) to include endotoxin removal (ER) for sensitive biology applications 2) a hardware/grocery store prodcut-based system for degreasing, sterilization, and ER for PS and other PP plastics 3) a basic lab equipment protocol for cell work, degreasing, sterilization and ER of glass replacing PS plastics. This project will test these protocols and develop or modify others covering a wide range of SUP's. It will also allow this team to demonstrate quality assurance of the resulting reuse systems, via endotoxin testing with a recombinant protein assay.